Proteostasis: Bad news and good news from the endoplasmic reticulum
The endoplasmic reticulum (ER) is an Sailing Vests intracellular compartment dedicated to the synthesis and maturation of secretory and membrane proteins, totalling about 30% of the total eukaryotic cells proteome.The capacity to produce correctly folded polypeptides and to transport them to their correct intra- or extracellular destinations relies